Stabilization of immunoglobulins and other proteins through aqueous formulations with sodium chloride at weak acidic to neutral pH

• 收藏
• 分享

专利权人:

BAXALTA INCORPORATED;BAXALTA GMBH;BAXTER HEALTHCARE S.A.

发明人:

BUTTERWECK, HARALD ARNO,BAUER, THERESA FRIEDERIKE,HOFBAUER, LUCIA,TESCHNER, WOLFGANG,ZOCHLING, OLIVER,SCHWARZ, HANS-PETER,MAYER, CHRISTA,HASSLACHER, MEINHARD

申请号：

AU2011301803

公开号：

AU2011301803A1

申请日:

2011.09.16

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention provides, among other aspects, storage stabile aqueous formulations of labile proteins at a mildly acidic to neutral pH. The present invention also provides methods for stabilizing a labile therapeutic protein composition at a mildly acidic to neutral pH. Advantageously, the methods and formulations provided herein allow stabile aqueous compositions of labile proteins at mildly acidic to neutral pH useful for parenteral administration.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/