Cosmetic use of at least one thiophene compounds as an active agent for treating and/or preventing oily skin and/or skin associated cosmetic defects in an individual, where the defects are e.g. skin imperfections caused by hyperseborrhea
BERNARD DOMINIQUE,DOMINIQUE BERNARD,THOMAS COLLIGNON AGNES,AGNES THOMAS COLLIGNON,ROZOT ROGER,ROGER ROZOT,MULLER BENOIT,BENOIT MULLER
申请号：
FR1060181
公开号：
FR2968199A1
申请日:
2010.12.07
申请国别(地区):
FR
年份:
2012
代理人:
摘要：
Cosmetic use of at least one thiophene compounds (I) and their salts as an active agent for treating and/or preventing oily skin and/or skin associated cosmetic defects, is claimed. Cosmetic use of at least one thiophene compounds of formula (I) and their salts as an active agent for treating and/or preventing oily skin and/or skin associated cosmetic defects, is claimed. n : 0 or 1； X : O or NH； either R1, R2 : H, -OH, -NH 2, F, 1-5C alkyl (optionally saturated and optionally interrupted by at least one heteroatoms of O, N or S), optionally saturated 5-10C cycloalkyl, or optionally saturated 5-10-membered ring comprising at least one heteroatoms of O, N or S； or R1R2 : optionally saturated 5-10 membered ring (optionally comprising at least one heteroatoms of O, N or S)； R3 : H, -OH, -NH 2, F, optionally saturated 1-5C alkyl, optionally saturated 5-10C cycloalkyl, 5-10-membered ring (optionally saturated and comprising at least one heteroatom of O, N or S), -OR11, -R11OH, -C(O)R11, -OC(O)R11, -C(O)OR11, -C(O)NH 2, -C(O)NH-R11, -C(O)NHR11R12, or NR11R12； R11, R12 : 1-5C alkyl (optionally saturated and optionally interrupted by at least one heteroatoms of O, N or S)； either R4 : H, -OH, -NH 2, F, optionally saturated 1-5C alkyl, -OR13, -R13OH, -C(O)R13, -OC(O)R13, -C(O)OR13, -C(O)NH 2, or -C(O)NH-R13； and R5 : H, -OH, -NH 2, F, optionally saturated 1-5C alkyl, -OR13, -R13OH, -C(O)R13, -OC(O)R13, -C(O)OR13, -C(O)NH 2, -C(O)NH-R13, or -(Y1) m-ZR14； or R4R5 : 3-8C cycloalkylene group； R13 : 1-5C alkyl group, preferably methyl or ethyl group； R14 : optionally saturated 5-10 membered ring (optionally comprising at least one heteroatoms of O, N or S)； and R6-R10 : H, -OH, -NH 2, fluorine, optionally saturated 1-5C alkyl, optionally saturated 5-10C cycloalkyl, -OR13, -R13OH, -C(O)R13, -OC(O)R13, -C(O)OR13, -C(O)NH 2, or -C(O)NH-R13. An independent claim is included for pharmaceutical or dermatological composition comprising (I) in a medium. [Image] ACTIVITY : Antiseborrheic；
