Tomasz Glinka,Olga Lomovskaya,Keith Bostian,David M. Wallace
申请号：
US12116164
公开号：
US08268865B2
申请日:
2008.05.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Disclosed are compounds having at least one quaternary alkyl ammonium functionality. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism.
