Tomasz Glinka,Robert Higuchi,Scott Hecker,Brian Eastman,Olga Rodny
申请号:
US13983747
公开号:
US20130316943A1
申请日:
2012.02.06
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed herein are polybasic bacterial efflux pump inhibitors containing boronic acid functionality and their methods of synthesis, methods of use, and pharmaceutical compositions. Some embodiments include methods of treating or preventing a bacterial infection by co-administering to a subject infected with bacteria or at risk of infection with bacteria the efflux pump inhibitor with another anti-bacterial agent.