PAN TZU MING,판 트주-밍,LEE CHUN LIN,리 춘-린,WU CHENG LUN,우 쳉-룬
申请号：
KR1020110093272
公开号：
KR1020130029890A
申请日:
2011.09.16
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A composite is provided to effectively lower blood fats, to enhance lipoprotein cholesterol concentration, and to prevent and treat vascular diseases and atherosclerosis.CONSTITUTION: A composite which lowers blood fats and enhances high density lipoprotein cholesterol contains monascin which is prepared by extracting from a fermented Monascus product. A method for preparing the composite comprises: a step of extracting the fermented Monascus product using acetone three times(102) a step of concentrating the extract by decompression to enhance extract concentration(103) and a step of isolating the extract by silica gel, column chromatography, silica gel, or high performance liquid chromatography and obtaining monascin and ankaflavin(104,105,106,107).COPYRIGHT KIPO 2013[Reference numerals] (101) Providing a fermented Monascus product (102) Repeatedly extracting the fermented Monascus product using acetone three times (103) Increasing the concentration of the product obtained from the previous step by decompression concentration in a predetermined temperature range (104) Isolating a pigment isolating solution by implementing a first isolating and purifying process for the product obtained from the previous step with silica gel column chromatography (105) Isolating a yellow pigment isolating solution by implementing a second isolating and purifying process for the pigment isolating solution obtained from the previous step with Sephadex LH-20 column chromatography (106) Isolating an isolating solution containing monascin and ankaflavin by implementing a third purifying process for the yellow pigment isolating solution obtained from the previous step with silica gel column chromatography (107) Isolating monascin components by implementing a fourth purifying process for the isolating solution containing monascin and ankaflavin obtained from the previous step with preparative high performance liquid chromatography (AA) Start (BB) End본 발명은 혈지방을 낮추고 고밀도 지방단백 콜레스테롤을
