Gaidul, Constantine Valentinovich,Dushkin, Aleksandr Valerevich
申请号：
AU2011304259
公开号：
AU2011304259B8
申请日:
2011.05.11
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2011304259B820120705.pdf#####ABSTRACT This invention is related to pharmacology, medicine, veterinary science and pharmaceutical industry. It particularly belongs to original composite antimicrobial and 5 vulnerary preparations for external administration production process, which poses a higher therapeutic efficiency in case of skin and soft tissues infections treatment. Proposed pharmaceutical compositions' active agents are fosfomicin and finely dispersed nanostructured silica dioxide. The mentioned pharmaceutical composition production 10 process includes mixing fosfomicin with finely dispersed nanostructured silica dioxide. It's main difference is that the mentioned substances mixture with weight ratio (25-75 mass.%) : (75-25 mass.%) respectively is being exposed to mechanical processing by impact and abrasive actions until fine powder fraction weight proportion increase (<； 5 micron) and becomes not less than 40%. 15
