LIMONOV VIKTOR LVOVICH,GAIDUL KONSTANTIN VALENTINOVICH,DUSHKIN ALEKSANDR VALEREVICH
申请号：
IN2987/CHENP/2012
公开号：
IN2012CN02987A
申请日:
2012.04.02
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
This invention is related to pharmacology, medicine, veterinary science and pharmaceutical industry. It particularly belongs to original composite antimicrobial preparations for parenteral administration production process, which poses a higher therapeutic efficiency in case of grave infection and inflammatory diseases. Proposed pharmaceutical compositions active agents are fosfomicin and finely dispersed nanostructured silica dioxide. The mentioned pharmaceutical composition production process includes mixing fosfomicin with finely dispersed nanostructured silica dioxide. Its main difference is that the mentioned substances mixture with weight ratio from 10:1 to 75:1 respectively is being exposed to mechanical processing by impact and abrasive actions until fine powder fraction weight proportion increase (< 5 micron) and becomes not less than 25%. The received mixture is used for injection preparation.
