The Regents of the University of Michigan;Indiana University Research and Technology Corporation
发明人:
Scott D. Larsen,Brandt C. Huddle,Kun Yang,Ronald Buckanovich,Thomas Hurley
申请号：
US16311533
公开号：
US20190255055A1
申请日:
2017.06.20
申请国别(地区):
US
年份:
2019
代理人:
摘要：
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a thiopyrimidinone structure which function as inhibitors of ALDH protein, and their use as therapeutics for the treatment of cancer and other diseases.
