Agent de contraste pour la détermination de l'activité d'aldéhyde déshydrogénase (ALDH)

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专利权人:

Cambridge Enterprise Limited

发明人:

申请号：

EP14150267.4

公开号：

EP2891500B1

申请日:

2014.01.07

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention describes a composition comprising deuterated 13 C ethanol for use in the determination of ALDH or ADH activity in vivo or in vitro. Aldehyde dehydrogenase is an emerging drug target for the treatment of heart disease, cocaine and alcohol dependence and conditions caused by genetic polymorphisms in ALDH. The present invention also describes a method for determining ALDH or ADH activity by 13 C-MR detection.

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中国工程科技知识中心

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http://www.ckcest.cn/home/