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Phenylacetamides and substituted phenylpropanamides and their use
专利权人:
Bayer Intellectual Property GmbH
发明人:
FÜRSTNER, Chantal,KELDENICH, Jörg,DELBECK, Martina,KOLKHOF, Peter,KRETSCHMER, Axel,POOK, Elisabeth,SCHMECK, Carsten,TRÜBEL, Hubert
申请号:
ES11758447
公开号:
ES2598279T3
申请日:
2011.09.14
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
Compound of formula (I) ** Formula ** in which A represents a bond or -C (R6AR6B) -, in which R6A represents hydrogen, (C1-C4) alkyl or trifluoromethyl, R6B represents hydrogen or (C1-) alkyl C4), R1 represents (C1-C6) alkyl, (C2-C6) alkenyl, (C2-C6) alkynyl or (C3-C7) cycloalkyl, wherein (C1-C6) alkyl, (C2-C6) alkenyl and (C2-C6) alkynyl may be substituted with 1 to 3 substituents independently selected from each other from the group consisting of deuterium, halogen, cyano, oxo, hydroxy, trifluoromethyl, cycloalkyl (C3-C7), alkoxy (C1-C6), trifluoromethoxy and phenyl, in which cycloalkyl (C3-C7) can be substituted with 1 or 2 substituents independently selected from each other from the group consisting of (C1-C4) alkyl, oxo, hydroxy, (C1-C4) alkoxy and amino , and wherein (C1-C6) alkoxy may be substituted with 1 or 2 substituents independently selected from each other from the group consisting of amino, hydroxy, (C1-C4) alkoxy, hydroxycar bonyl and alkoxycarbonyl (C1-C4) and in which phenyl may be substituted with 1 to 3 substituents independently selected from each other from the group consisting of halogen, cyano, nitro, (C1-C4) alkyl, trifluoromethyl, hydroxy, hydroxymethyl , (C1-C4) alkoxy, trifluoromethoxy, (C1-C4) alkoxymethyl, hydroxycarbonyl, alkoxycarbonyl (C1-C4), aminocarbonyl, monoalkylaminocarbonyl (C1-C4) and dialkylaminocarbonyl (C1-C4), and in which cycloalkyl (C3- C7) may be substituted with 1 or 2 substituents independently selected from each other from the group consisting of fluorine, (C1-C4) alkyl, (C1-C4) alkoxy, hydroxy, amino and oxo, R2 represents benzothienyl, phenyl, thienyl or furyl, in which benzothienyl, phenyl, thienyl and furyl may be substituted with 1 to 3 substituents independently selected from each other from the group consisting of halogen, cyano, nitro, (C1-C4) alkyl, trifluoromethyl, hydroxy, (C1) alkoxy -C4) and trifluoromethoxy, R3 represents a g rupo of formula ** Formula ** in which it represents the point of attachment t
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