NTI-ADDAE, KWAME W.,WALDO, MICHAEL,ONEIL, SIMON ADAM,VAN ALSTEN, JOHN GREGG,MACIKENAS, DAINIUS,MUDUNURI, PRAVEEN,SHI, YI,LEDEBOER, MARK WILLEM,JURKAUSKAS, VALDAS,MEDEK, ALES,JONES, STEVEN,BYRN, RANDAL
申请号:
CA2930103
公开号:
CA2930103A1
申请日:
2014.11.12
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Polymorphic forms of Compound (1) or a pharmaceutically acceptable salt thereof, wherein Compound (1) is represented by the following structural formula: are Form A of HCl salt of Compound (1)·1/2?20, Form F of HCl salt of Compound (1)·3?20, Form D of HCl salt of Compound (1), Form A of Compound (1), and Form A of tosylate salt of Compound (1). Such polymorphic forms are employed for treating influenza, inhibiting the replication of influenza viruses, or reducing the amount of influenza viruses in a biological sample or in a subject.