Kwame W. Nti-Addae,Michael Waldo,Simon Adam ONeil,John Gregg Van Alsten,Dainius Macikenas,Praveen Mudunuri,Yi Shi,Mark Willem Ledeboer,Valdas Jurkauskas,Ales Medek,Steven Jones,Randal Byrn,Mohammed As
申请号：
US15150459
公开号：
US09771361B2
申请日:
2016.05.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Polymorphic forms of Compound (1) or a pharmaceutically acceptable salt thereof, wherein Compound (1) is represented by the following structural formula:are Form A of HCl salt of Compound (1).½H2O, Form F of HCl salt of Compound (1).3H2O, Form D of HCl salt of Compound (1), Form A of Compound (1), and Form A of tosylate salt of Compound (1). Such polymorphic forms are employed for treating influenza, inhibiting the replication of influenza viruses, or reducing the amount of influenza viruses in a biological sample or in a subject.
