University of Pittsburgh - Of the Commonwealth System of Higher Education
发明人:
Seema S. Lakdawala,Nara Lee
申请号：
US16480240
公开号：
US20190367923A1
申请日:
2018.01.22
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Antisense oligonucleotides (ASOs) that disrupt RNA-RNA interactions of influenza virus genome segments that are required for virus packaging are described. The ASOs can be used to inhibit influenza A virus replication in vitro and in vivo. Use of the ASOs for the treatment of a subject with an influenza virus infection is also described.
