Paul S. Charifson,Michael P. Clark,Upul K. Bandarage,Randy S. Bethiel,Michael J. Boyd,Ioana Davies,Hongbo Deng,John P. Duffy,Luc J. Farmer,Huai Gao,Wenxin Gu,Joseph M. Kennedy,Brian Ledford,Mark W. Le
申请号:
US14666567
公开号:
US09394302B2
申请日:
2015.03.24
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This invention provides methods of preparing 3-(pyrimidin-2-yl)-1H-pyrrolo[2,3-b]pyridines and 3-(pyrimidin-2-yl)-1H-pyrazolo[3,4-b]pyridines, or pharmaceutically acceptable salts thereof that are useful for inhibiting the replication of influenza viruses in a biological sample or patient, reducing the amount of influenza viruses in a biological sample or patient, and treating influenza in a patient.