The invention discloses a deer blood wine for improving immunity of the organism, which is characterized in that the deer blood wine is made from 1 to 15 parts by weight of deer blood, 60 to 200 parts by weight of yam, 30 to 90 parts by weight of tuckahoe, 30 to 90 parts by weight of wolfberry fruit, 10 to 40 parts by weight of ginseng, radix codonopsitis or American ginseng, 300 to 800 parts by weight of liquor and 50 to 400 parts by weight of purified water which serve as raw materials with the parts by weight:. The invention further discloses a method for the deer blood wine. The deer blood wine is a new healthcare wine with simple formula and good taste, and has the healthcare function of improving immunity of the organism the preparation method of the deer blood wine is scientific and advanced, and can effectively extract the effective components from the raw materials, and remove impurities thus the prepared deer blood wine is tasty and has no obvious medicinal odor.