The present invention addresses the problem of providing a novel proliferation material which enables the proliferation of Akkermansia muciniphila. An Akkermansia muciniphila proliferation material containing at least one polyphenol component selected from the group consisting of quercetin glycoside, isorhamnetin, cyanidin glucoside, hesperetin, hesperidin, apigenin, chrysin, tangeretin, nobiletin and tannic acid.本發明之目的在於提供一種可使嗜粘蛋白阿克曼氏菌(Akkermansia muciniphila)增殖之新穎之增殖材料。本發明之嗜粘蛋白阿克曼氏菌之增殖材料含有選自由槲皮素醣苷、異鼠李素(Isorhamnetin)、花青基葡萄糖苷、柑果苷素(hesperetin)、橙皮苷(hesperidin)、洋元荽黃素(apigenin)、金黃酮(chrysin)、桔皮素(tangeretin)、陳黃皮酮(nobiletin)、及單寧酸所組成之群中之一種以上之多酚。