The present invention relates to alpha hydroxy amides including compounds of formula I and related compounds and their use in the prophylaxis and treatment of inflammatory disorders and diseases, wherein: T1 denotes one of the following groups: T2-W denotes one of the following groups: W denotes a single bond, or a group selected from &mdash；CHRc&mdash； and &mdash；CH&boxH；CH&mdash；； and RW denotes a group selected from H, Hal, linear or branched alkyl, Ar, Het, Cyc, &mdash；(CH2)nAr, &mdash；(CH2)nHet, &mdash；(CH2)nCyc, &mdash；(CH2)nOAr, &mdash；(CH2)nOHet, &mdash；(CH2)nOCyc, or A.La présente invention concerne des alpha-hydroxy-amides, comprenant des composés de formule (I) et des composés apparentés ainsi que leur utilisation dans la prophylaxie et le traitement de troubles et maladies inflammatoires, T1, T2, W et Rw ayant la définition indiquée dans la revendication 1.
