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ALPHA ALKYLATION D'ALDÉHYDE AVEC UNE OLÉFINE POLYCYCLIQUE
专利权人:
Firmenich SA
发明人:
申请号:
EP18716644.2
公开号:
EP3612510A1
申请日:
2018.04.17
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to the field of organic synthesis and more specifically to the alpha alkylation of an aldehyde with a polycyclic olefin followed by a ring opening step in order to provide compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof and wherein R represents a hydrogen atom or C1-8 linear alkyl group; R1, R2, R3 and R4 represent, when taken separately, independently of each other, a hydrogen atom or a C1-2 linear alkyl group or a C3-4 linear or branched alkyl group; or R2 and R3, when taken together, represent a C4-10 linear, branched or cyclic alkanediyl group and n is 1 or 2.
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