GEIERSTANGER, Bernhard Hubert,OU, Weijia,UNO, Tetsuo
申请号:
HK16101565.5
公开号:
HK1213580A
申请日:
2016.02.12
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention provides specific sites for modifying antibodies or antibody fragments by replacing at least one native amino acid in the constant region of a parental antibody or antibody fragment with cysteine, which can be used as a site of attachment for a payload or linker-payload combination.