GEIERSTANGER, Bernhard Hubert,OU, Weijia,UNO, Tetsuo
申请号:
AU2017219059
公开号:
AU2017219059A1
申请日:
2017.08.24
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
#$%^&*AU2017219059A120170914.pdf#####Abstract The present invention provides specific sites for modifying antibodies or antibody fragments by replacing at least one native amino acid in the constant region of a parental antibody or antibody fragment with cysteine, which can be used as a site of attachment for a payload or linker-payload combination.