Geierstanger, Bernhard Hubert,Ou, Weijia,Uno, Tetsuo
申请号：
AU2014214751
公开号：
AU2014214751B2
申请日:
2014.02.07
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The present invention provides specific sites for modifying antibodies or antibody fragments by replacing at least one native amino acid in the constant region of a parental antibody or antibody fragment with cysteine, which can be used as a site of attachment for a payload or linker-payload combination.
