SPECIFIC SITES FOR MODIFYING ANTIBODIES TO MAKE IMMUNOCONJUGATES

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专利权人:

Weijia OU;Bernhard Hubert GEIERSTANGER;Tetsuo UNO

发明人:

Bernhard Hubert GEIERSTANGER,Weijia OU,Tetsuo UNO

申请号：

US14764026

公开号：

US20160067351A1

申请日:

2014.02.07

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention provides specific sites for modifying antibodies or antibody fragments by replacing at least one native amino acid in the constant region of a parental antibody or antibody fragment with cysteine, which can be used as a site of attachment for a payload or linker-payload combination.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/