MUKERJI PRADIP,LEONARD AMANDA EUN-YEONG,HUANG YUNG-SHENG,THURMOND JENNIFER,KIRCHNER STEPHEN J,PARKER-BARNES JENNIFER M,DAS TAPAS
申请号：
JP20110014983
公开号：
JP2011139703(A)
申请日:
2011.01.27
申请国别(地区):
日本
年份:
2011
代理人:
摘要：
PROBLEM TO BE SOLVED: To identify four genes involved in an elongation of polyunsaturated acid (i.e., "elongase"); and to provide a use thereof. SOLUTION: Two of four genes involved in an elongation of polyunsaturated acid (i.e., "elongase") are also involved in the elongation of monounsaturated fatty acids. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomogama linolenic acid (DGLA) and in the conversion of DGLA or 20:4n-3 to eicosapentaenoic acid (EPA). DGLA may be utilized in the production of polyunsaturated fatty acids, such as arachidonic acid (AA), docosahexaenoic acid (DHA), EPA, adrenic acid,ω6-docosapentaenoic acid orω3-docosapentaenoic acid, added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics. COPYRIGHT: (C)2011,JPO&INPIT
