CHAO, YU CHAN,赵裕展,趙裕展,WU, YUEH LUNG,吴岳隆,吳岳隆,WU, CAROL PEIYIN,吴佩颖,吳佩穎
申请号：
TW101106106
公开号：
TWI487710B
申请日:
2012.02.23
申请国别(地区):
TW
年份:
2015
代理人:
摘要：
The present invention provides nucleic acid molecules for suppressing of DNA replication, wherein the nucleic acids are introduced into a cell and binding toorisequence of the plasmid or virus. In particular, the present invention features nucleic acid molecules such as miRNA or RNAi and methods to block the infection and/or latent infection of Epstein-Barr virus and affects baculovirus replication.本發明係提供一種調控DNA複製之核酸分子,其中該核酸分子係被送入細胞內且與基因或病毒DNA的複製起始點結合。該核酸分子可為微小RNA(miRNA)或干擾性RNA(RNAi)。本發明已證明可用於專一性調控潛伏EB病毒及桿狀病毒之複製與調控質體之基因複製。
