1. A method for the treatment of active tuberculosis infection in a mammal, comprising the step of administering to a mammal having active infection tuberculosis an immunologically effective amount of a therapeutic vaccine in combination with one or more chemotherapeutic agents, wherein the vaccine comprises a pharmaceutical composition comprising an isolated fusion polypeptide wherein the fusion polypeptide comprises ( a) combination of antigen Rv1813, Rv3620 and Rv2608 Mycobacterium species of the tuberculosis complex, and the antigens are covalently linked, or (b) pos edovatelnost having at least 90% identity with the combination antigenov.2. A method according to Claim. 1, where the therapeutic vaccine comprising a fusion polypeptide comprising (a) a combination of mycobacterial antigen Rv2608, Rv3619, Rv3620 and Rv1813 or (b) a sequence having at least 90% identity with the combination antigenov.3. A method according to claim. 2, wherein the mycobacterial antigen Rv2608, Rv3619, Rv3620 and Rv1813 is an antigen Rv2608, Rv3619, Rv3620 and Rv1813 MV tuberculosis.4. A method according to claim 3, wherein the fusion polypeptide comprises the amino acid sequence shown in SEQ ID NO:. 1, or a sequence having at least 90% identity with ney.5. A method according to claim 3, wherein the fusion polypeptide comprises the amino acid sequence shown in SEQ ID NO:. 2, or a sequence having at least 90% identity with ney.6. A method according to Claim. 1, where the therapeutic vaccine comprising a fusion polypeptide comprising (a) a combination of mycobacterial antigen Rv2608, Rv3620 and Rv1813 or (b) a sequence having at least 90% identity with the combination antigenov.7. A method according to claim. 6, wherein the antigen of mycobacteria Rv2608, Rv3620 and Rv1813 is an antigen Rv2608, Rv3620 and Rv1813 MV tuberculosis.8. . A method according to claim 6, wherein the fusion polypeptide comprises the amino acid sequence shown in SEQ ID NO: 3 or SEQ ID NO: 4, or1. Способ лечения а
