Zoller, Mark T.,Li, Xiaodong,Staszewski, Lena,O'Connell, Shawn,Zozulya, Sergey,Adler, Jon Elliot,Xu, Hong,Echeverri, Fernando
申请号：
ES10180331
公开号：
ES2587610T5
申请日:
2002.06.26
申请国别(地区):
ES
年份:
2020
代理人:
摘要：
An in vitro method for identifying a cell that is potentially sensitive to taste stimuli sweets, the method comprising: (a) detecting expression of a polypeptide of T1R2 and / or a nucleic acid encoding said polypeptide T1R2 by said cell, wherein said T1R2 polypeptide (i) is encoded by a nucleic acid sequence comprising SEQ ID NO: 10 or a sequence having at least 90% sequence identity with SEQ ID NO: 10； or (ii) has at least 90% sequence identity with the polypeptide of T1R2 of SEQ ID NO: 6； and (b) detecting expression of a polypeptide of T1R3 and / or a nucleic acid encoding said polypeptide T1R3 by said cell, wherein said polypeptide of T1R3 (i) is encoded by a nucleic acid sequence comprising SEQ ID NO : 9 or a sequence having at least 90% sequence identity with SEQ ID NO: 9； or (ii) has at least 90% sequence identity with the polypeptide of T1R3 of SEQ ID NO: 7.
