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METHOD AND KIT FOR PREDICTING ANTIBODY THERAPY
专利权人:
发明人:
申请号:
EP15186178.8
公开号:
EP3026123A1
申请日:
2007.04.27
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Methods are provided for determining the responsiveness of, in particular classifying, a patient to a therapy, such as an antibody therapy, e.g.rituximab, and for selecting and/or for treating a subject based on both the H/R 131 FcγRIIA polymorphism and the V/F 158 FcγRIIIA polymorphism. Kits for carrying out the method and methods for optimizing antibody therapies patients based on the responsiveness are also provided. Methods for providing a reference index for correlating treatment response to the nine genotypes are also claimed.
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