SHANGHAI ALLIST PHARMACEUTICALS AND MEDICAL TECHNOLOGY CORPORATIONS
发明人:
Rongren Kuang
申请号:
US16307362
公开号:
US20190218213A1
申请日:
2017.06.01
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to the fused pyrimidine piperidine cyclic derivative represented by the following formula (I) and a pharmaceutically acceptable salt thereof and a process for preparing the same, wherein R1, R2, R3, R4, R5, X, Y and Z are defined as in the description. The present invention further provides use of said fused pyrimidine piperidine cyclic derivative in manufacture of a medicament for preventing or treating FGFR kinase mediated disease such as cancer.