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CAMPTOTHECIN DERIVATIVES HAVING ANTITUMOR ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
专利权人:
ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI;SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
发明人:
PENCO, SERGIO,MERLINI, LUCIO,ZUNINO, FRANCO,CARMINATI, PAOLO
申请号:
HU0200210
公开号:
HU229506B1
申请日:
2000.03.08
申请国别(地区):
HU
年份:
2014
代理人:
摘要:
Derivatives of camptothecin of formula (I) <;CHEM>; wherein the groups R1, R2 and R3 are as defined in the description are disclosed. The compounds of formula (I) are endowed with antitumor activity and show a good therapeutic index. Processes for the preparation of the compounds of formula (I) and their use in the preparation of medicaments useful in the treatment of tumors are also disclosed.
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