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Boronoftalide biocide compounds
专利权人:
ANACOR PHARMACEUTICALS; INC.
发明人:
BAKER, STEPHEN,AKAMA, TSUTOMU,BELLINGER-KAWAHARA, CAROLYN,HERNANDEZ, VINCENT,HOLD, KARIN,LEYDEN, JAMES,MAPLES, KIRK,PLATTNER, JACOB,SANDERS, VIRGINIA,ZHANG, YONG-KANG
申请号:
ES11154575
公开号:
ES2540966T3
申请日:
2006.02.16
申请国别(地区):
ES
年份:
2015
代理人:
摘要:
A compound for therapeutic use, the compound has a structure according to Formula (IIb): ** Formula ** wherein R7b is an element selected from H, methyl, ethyl and phenyl; R10b is an element selected from H, OH, NH2, SH, halogen, substituted or unsubstituted phenoxy, substituted or unsubstituted phenylalkyl, substituted or unsubstituted phenylthio and substituted or unsubstituted phenylalkyl; and R11b is an element selected from H, OH, NH2, SH, methyl, substituted or unsubstituted phenoxy, substituted or unsubstituted phenylalkyl, substituted or unsubstituted phenylthio and substituted or unsubstituted phenylalkyl wherein the term "alkyl" is a group C1-C10 alkyl; wherein the substituents for the various alkyl groups listed are selected from: -OR ',>; = O,>; = NR',>; = N-OR ', -NR'R ", -SR', -halogen, -OC ( O) R ', -C (O) R', -CO2R '-CONR'R ", - OC (O) NR'R", -NR "C (O) R', -NR'-C (O) NR "R" ', -NR "C (O) 2R', -NR-C (NR'R" R "')>; = NR" ", -NR-C (NR'R")>; = NR "' , -S (O) R ', -S (O) 2R', - S (O) 2NR'R ", -NRSO2R ', -CN and -NO2 in a number that ranges from zero to (2m' + 1) , where m 'is the total number of carbon atoms in such a radical, and where R', R ", R" 'and R " each independently refer to hydrogen, heteroalkyl, aryl, alkyl, alkoxy, thioalkoxy groups or arylalkyl; and wherein the substituents for the various aryl groups listed are selected from the group consisting of: halogen, -OR ',>; = O,>; = NR',>; = N-OR ', -NR'R ", -SR' , -OC (O) R ', -C (O) R', -CO2R ', -CONR'R ", - OC (O) NR'R", -NR "C (O) R', -NR ' -C (O) NR "R" ', - NR "C (O) 2R', -NR-C (NR'R" R "')>; = NR" ", -NR-C (NR'R") >; = NR "', - S (O) R', -S (O) 2R ', - S (O) 2NR'R", -NRSO2R', -CN and -NO2, -R ', -N3, - CH (Ph) 2, fluoro (C1-C4) alkoxy, and fluoro (C1-C4) alkyl, in a number ranging from zero to the total number of open valences; and where R ', R ", R"' and R " are independently selected from hydrogen, alkyl, heteroalkyl, aryl and heteroaryl.Un compuesto para uso terapé
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