Formula (i):< Conversion 1 >(In formula,As for R1 and R3 becoming independent, H F Cl Br - NO2 - CN F or C1 - C6 alkyl groups which are possible to be substituted optionally with Cl Or, displaying C1 - C6 alkoxy groups which are possible to be substituted optionally with F,2 value which as for R4 carbon acid radical (- COOH) or that ester, or - C (=O) NR6 R7, - NR7 C (=O) R6, - NR7 C (=O) OR6, - NHC (=O) NR7 R6 or - NHC (=S) NR7 R6 (here, as for R6 H or formula - (Alk) the basis of m-Q (here, as for m 0 or 1 is, as for Alk is possible to be substituted optionally direct or C1 - C12 alkylenes of ramification or C2 - C12To be arukeniren or C2 - C12 arukiniren bases or C3 - C12 carbon cyclic bases of 2 value, these bases, one or more - O-, - S-MATAHA-N (R8) - connection (here, H or C1 - C4 alkyls, C3 - C4 arukeniru, C3 - C4 arukiniru or C3 - C6 shikuroarukiru are displayed,) have been allowed to have possessed R8, and as for Q H, - NR9 R10 (here, as for R9 and R10 becoming independent, H C1 - C4 alkyls C3 - C4 arukeniru C3 - C4 arukiniru C3 - C6 shikuroarukiru Ester basis The carbon cyclic basis or the complex cyclic basis which are possible to be substituted optionally are displayed, or or R9 and R10 the nitrogen which those have connected and becoming simultaneous, forms ring, as for that ring is possible to be substituted) displays optionally) displaying,R7 displays H or C1 - C6 alkyls, or or R6 and R7 one or the plural atoms which those have connected and becoming simultaneous, forms the complex ring of the single cyclic type which possesses the ring atom of 5, 6 or 7 where it is possible to be substituted optionally) to display, andX the connection hand or formula - (Z) n- (Alk) - or - (Alk) - (Z) n- (here, - O-, - S-MATAHA-NH-WO displays Z, Alk is as defined in regard to R6, n 0 or 1 is) is the basis of 2 value)Chemical compound is the inhibiter of CD80, is useful in immunity adjustment remedy.式(I):【化1】(式中、R1およびR3は独立して、H;F;Cl;Br;-NO2;-CN;FもしくはClで任意に置換されていてもよいC1-C
