Heterobicyclo-substituted-[1,2,4]triazolo[1,5-c]quinazolin-5-amine compounds with A2A antagonist properties

• 收藏
• 分享

专利权人:

Merck Sharp & Dohme Corp.

发明人:

Ali, Amjad,Lo, Michael Man-Chu,Lim, Yeon-Hee,Stamford, Andrew,Kuang, Rongze,Tempest, Paul,Yu, Younong,Huang, Xianhai,Henderson, Timothy J.,Kim, Jae-Hun,Boyce, Christopher,Ting, Pauline,Zheng, Junying

申请号：

AU2013370977

公开号：

AU2013370977A1

申请日:

2013.12.20

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

Disclosed are compounds of Formula Gl (structurally represented): where "RG3" "Rd1" to "Rd4", "n", "m", "p", "W", "X", "Y", and "Z" are defined herein which compounds are antagonists of A2A receptor. Disclosed herein also are uses of the compounds described herein as antagonists of the A2a receptor in the potential treatment or prevention of neurological disorders and diseases in which A2A receptors are involved. Disclosed herein also are pharmaceutical compositions comprising these compounds and uses of these pharmaceutical compositions.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/