JUNE, CARL, H.,LEVINE, BRUCE, L.,PORTER, DAVID, L.,KALOS, MICHAEL, D.,MILONE, MICHAEL C.
申请号:
EP11846757
公开号:
EP2649086A4
申请日:
2011.12.09
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.