Carl H. June,Bruce L. Levine,David L. Porter,Michael D. Kalos,Michael C. Milone
申请号:
US14107302
公开号:
US09328156B2
申请日:
2013.12.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.