June, Carl H.,Levine, Bruce L.,Porter, David L.,Kalos, Michael D.,Milone, Michael C.
申请号：
AU2017225161
公开号：
AU2017225161B2
申请日:
2017.09.10
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
#$%^&*AU2017225161B220191121.pdf#####The present invention provides genetically modified T cells in compositions and methods for treating cancer in a human. The invention includes administering a chimeric antigen receptor (CAR) that genetically modifies T cell to express the CAR. The CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signalling region, and a CD3 zeta signalling domain.
