The Trustees of The University of Pennsylvania;UNIV PENNSYLVANIA
发明人:
申请号:
EP17153799.6
公开号:
EP3214091B1
申请日:
2011.12.09
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.