The Trustees of The University of Pennsylvania Center for Technology Transfer
发明人:
JUNE Carl H.,LEVINE Bruce L.,PORTER David L.,KALOS Michael D.,MILONE Michael C.
申请号：
SI201131301
公开号：
SI2649086T1
申请日:
2011.12.09
申请国别(地区):
SI
年份:
2018
代理人:
摘要：
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.
