2- [4- (PYRAZOL-4-YLALKYL) PIPERAZIN-1-YL] -3-PHENYL-PYRAZINES AND PYRIDINES AND 3- [4- (PYRAZOL-4-YLALKYL) PIPERAZIN-1-YL] -2-PHENYL -PYRIDINES AS 5-HT7 RECEPTOR ANTAGONISTS

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专利权人:

ELI LILLY AND COMPANY

发明人:

BADESCU, VALENTINA, O.,CAMP, ANNE, MARIE,CLARK, BARRY, PETER,COHEN, MICHAEL, PHILIP,FILLA, SANDRA, ANN,GALLAGHER, PETER, THADDEUS,HELLMAN, SARAH, LYNNE,MAZANETZ, MICHAEL, PHILIP,PINEIRO-NUNEZ, MARTA,

申请号：

DK08747748

公开号：

DK2155717T3

申请日:

2008.05.07

申请国别(地区):

DK

年份:

2012

代理人:

摘要：

The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently &mdash；C(H)&boxH； or &mdash；N&boxH；, provided that at least one of A and B is &mdash；N&boxH；, n is 1-3, m is 0-3, and R1-4 are as defined herein.

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http://www.ckcest.cn/home/