SONG, DAE HAE,LIM, CHANG KI,SONG, TAE HUN,KIM, YOUNG HOON,KWON, SE CHANG,LEE, GWAN SUN,JUNG, SUNG YOUB,CHOI, IN YOUNG
申请号：
CA2674538
公开号：
CA2674538C
申请日:
2008.01.04
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to an insulinotropic peptide conjugate having improved in-vivo duration of efficacy and stability, comprising an insulinotropic peptide, a non-peptide polymer and an immunoglobulin Fc region, which are covalently linked to each other, and a use of the same. The insulinotropic peptide conjugate of the present invention has the in-vivo activity which is maintained relatively high, and has remarkably increased blood half- life, and thus it can be desirably employed in the development of long acting formulations of various peptide drugs.
