DAE HAE SONG;CHANG KI LIM;TAE HUN SONG;YOUNG HOON KIM;SE CHANG KWON;GWAN SUN LEE;SUNG YOUB JUNG;IN YOUNG CHOI;HANMI SCIENCE CO. LTD.;HANMI SCIENCE CO. LTD.
发明人:
DAE HAE SONG,CHANG KI LIM,TAE HUN SONG,YOUNG HOON KIM,SE CHANG KWON,GWAN SUN LEE,SUNG YOUB JUNG,IN YOUNG CHOI
申请号：
IL19956609
公开号：
IL199566A
申请日:
2009.06.25
申请国别(地区):
IL
年份:
2016
代理人:
摘要：
The present invention relates to an insulinotropic peptide conjugate having improved in-vivo duration of efficacy and stability, comprising an insulinotropic peptide, a non-peptide polymer and an immunoglobulin Fc region, which are covalently linked to each other, and a use of the same. The insulinotropic peptide conjugate of the present invention has the in-vivo activity which is maintained relatively high, and has remarkably increased blood half-life, and thus it can be desirably employed in the development of long acting formulations of various peptide drugs.
