The present invention relates to antibody comprising human antibody and its antigen-binding portion thereof in conjunction with P- cadherin antibodies, and play the effect for inhibiting P- cadherins. The invention further relates to heavy chains and light chain immunoglobulins from people's P- cadherin antibodies, and encode the nucleic acid molecules of this immunoglobulin like protein. The invention further relates to the method for manufacturer's P- cadherin antibodies, the composition comprising these antibody and use the method for the antibody and composition. The invention further relates to transgenic animals or plant comprising nucleic acid molecules of the present invention.本發明涉及抗體，其包括人抗體及其抗原結合部分，其結合P-鈣黏着蛋白抗體，並且發揮抑制P-鈣黏着蛋白的作用。本發明還涉及來自人P-鈣黏着蛋白抗體的重鏈和輕鏈免疫球蛋白，以及編碼這類免疫球蛋白的核酸分子。本發明還涉及製造人P-鈣黏着蛋白抗體的方法、包含這些抗體的組合物和使用所述抗體和組合物的方法。本發明還涉及包含本發明核酸分子的轉基因動物或植物。
