DÉRIVÉ DE CATÉCHOL MARQUÉ PAR 11C, SONDE DE TOMOGRAPHIE PAR ÉMISSION DE POSITONS (TEP) POUR INHIBITEUR D'AGRÉGATION DE TAU PHOSPHORYLÉ UTILISANT CELUI-CI, ET PROCÉDÉS DE PRODUCTION ASSOCIÉS

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专利权人:

National Center for Geriatrics and Gerontology

发明人:

SUZUKI, Masaaki,ITO, Kengo,KATO, Takashi,IKENUMA, Hiroshi,KOYAMA, Hiroko

申请号：

EP17824156

公开号：

EP3482775A4

申请日:

2017.06.30

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

An object of the invention is to provide an 11 C-labeled catechol derivative having sufficient radioactivity to obtain an imaging image by a PET apparatus, a PET probe of a phosphorylated tau aggregation inhibitor using the same, and a method for producing them. The 11 C -labeled catechol derivative of the present invention is represented by the following general formula (a) (wherein R is a substituent having an isopropylamino group, and the carbon at the 2-position of the isopropylamino group is labeled with 11 C).

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中国工程科技知识中心

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http://www.ckcest.cn/home/