Philippe Barthelemy,Khalid Oumzil,Palma Rocchi,Julie Acunzo
申请号:
US14895277
公开号:
US20160108398A1
申请日:
2014.06.05
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention concerns an oligonucleotide modified by substitution at the 3′ or the 5′ end by a moiety comprising at least one ketal functional group, wherein the ketal carbon of said ketal functional group bears two saturated or unsaturated, linear or branched, hydrocarbon chains comprising from 1 to 22 carbon atoms, and the use therefore as a medicament, in particular for use for treating cancer.