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Migrastatin analogs in the treatment of cancer
专利权人:
David C. Dorn;Kaida Wu;Samuel J. Danishefsky;Jón T. Njardarson;Mihirbaran Mandal;Malcolm A. S. Moore;Christoph Gaul
发明人:
Samuel J. Danishefsky,Christoph Gaul,Jón T. Njardarson,Malcolm A. S. Moore,Kaida Wu,David C. Dorn,Mihirbaran Mandal
申请号:
US11597678
公开号:
US08957056B2
申请日:
2005.05.25
申请国别(地区):
US
年份:
2015
代理人:
摘要:
In one aspect, the present invention provides a method for treating colon and/or ovarian cancer in a subject comprising administering to a subject in need thereof a compound of general formula (I): wherein R1-R6, R, -R, Q, Y1, Y2 and n are as defined herein, wherein the compound is present in an amount effective to inhibit colon and/or ovarian tumor metastasis.
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