ROBERTS, MICHAEL S.,LORENCE, ROBERT M.,GROENE, WILLIAM S.,RABIN, HARVEY,VON BORSTEL, REID W.
申请号：
CA2305269
公开号：
CA2305269C
申请日:
1998.10.09
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The subject invention relates to viruses that are able to replicate andthereby kill neoplastic cells with a deficiency in the IFN-mediated antiviralresponse, and their use in treating neoplastic disease including cancer andlarge tumors. RNA and DNA viruses are useful in this regard. The inventionalso relates to methods for the selection, design, purification and use ofsuch viruses for cancer therapy.
