DODD STEPHANIE KAY,FURET PASCAL,GROTZFELD ROBERT MARTIN,JONES DARRYL BRYNLEY,MANLEY PAUL,MARZINZIK ANDREAS,PELLE XAVIER FRANCOIS ANDRE,SALEM BAHAA,SCHOEPFER JOSEPH
申请号:
IN9758/DELNP/2014
公开号:
IN2014DN09758A
申请日:
2014.11.18
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention relates to compounds of formula (I): in which Y,Y,R,R,R and R are defined in the Summary of the Invention capable of inhibiting the activity of BCR ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.