BLAKEMORE, STEPHEN J.,DI BACCO, ALESSANDRA M.,MULLIGAN, GEORGE J.
申请号:
CA2862320
公开号:
CA2862320A1
申请日:
2013.01.23
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention provides a method of treating nasopharyngeal cancer with a proteasome inhibitor of formula (7). The invention also provides a method of treating a patient with nasopharyngeal cancer based on elevated expression levels of NFkB, as measured by a H-score of the patients nasopharyngeal cancer tumor sample using a "NFkB p65 IHC assay. The invention also provides a method of determing whether to treat a patient with the compound of formula (/) based on the level of NFkB p65 in the patients nasopharyngeal cancer tumor sample.