Stephen J. Blakemore,Alessandra M. Di Bacco,George J. Mulligan
申请号：
US15358400
公开号：
US20170157155A1
申请日:
2016.11.22
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides a method of treating nasopharyngeal cancer with a proteasome inhibitor of formula (7). The invention also provides a method of treating a patient with nasopharyngeal cancer based on elevated expression levels of NFkB, as measured by a H-score of the patients nasopharyngeal cancer tumor sample using a “NFkB p65 IHC assay. The invention also provides a method of determining whether to treat a patient with the compound of formula (/) based on the level of NFkB p65 in the patients nasopharyngeal cancer tumor sample.
