TRIPETIDE BORONIC ACID OR BORONIC ESTER, PREPARATIVE METHOD AND USE THEREOF

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专利权人:

Runtao Li;Yongqiang Zhu;Zemei Ge;Shuyang Yao;Tieming Cheng;Jingrong Cui

发明人:

Runtao Li,Jingrong Cui,Yongqiang Zhu,Shuyang Yao,Zemei Ge,Tieming Cheng

申请号：

US13379142

公开号：

US20120135921A1

申请日:

2010.05.17

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention discloses proteasome inhibitors of tripeptide boronic acids or boronic esters represented by Formula (I), preparative method and use thereof. The proteasome inhibitors are therapeutical agents for treating malignant tumor, various nervous system degenerative diseases, muscle cachexia or diabetes, wherein the malignant tumor is leukemia, gastric cancer, hepatocarcinoma or nasopharyngeal carcinoma.

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