SUNNYBROOK RESEARCH INSTITUTE;THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
发明人:
RICHARD CHENG,GERTRAUD EYLERT,SIJIN HE,JEAN-MICHEL GARIÉPY,NAVID HAKIMI,MARC G. JESCHKE,AXEL GUENTHER
申请号：
US16517388
公开号：
US20200023172A1
申请日:
2019.07.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed herein is an instrument that enables the in situ formation of architected planar biomaterials and tissues by translating a printer head along a deposition surface such as a patient having burn injuries. In handheld embodiments of the instrument, cell-laden biopolymer solutions are perfused through a moving microfabricated printer head and deposited onto a stationary planar surface or a wound. The printer head may be translated via a drive mechanism. A soft deformable roller mitigates further damage to the injured area of skin as it rolls over it and a gimbal mechanism to which the printer head is attached is in contact with the injured tissue but is configured so that the printer head while in contact with tissue, does not exert undue pressure on the would area.
